1.Pharmacokinetics: Oral administration begins to work in 10 to 30 minutes. Absorption is good. The drug reaches a peak of action in 60 to 90 minutes and last for 4 to 8 hours.
2. Actions of the medication: Glycerin is used to reduce the Intraocular pressure (IOP) by creating an osmotic gradient in between the plasma and ocular fields.
3. Use: Temporarily reduces IOP in acute attacks of glaucoma. It is also prescribed for reduction of IOP prior to surgery.
4. Adverse effects: Decreased fluid volume. The most serious of these conditions is hyperosmolar nonketotic coma. Other adverse affects are confusion, syncope, cardiac dysrhythmias, nausea, vomiting and sever dehydration.
5. Contraindications: Severe dehydration, abdominal pain, appendicitis, pulmonary edema, and severe cardiac decompensation.
6. Nursing Implications: Important to check the therapeutic effects indicated by a reduction in IOP. The nurse should check the fluid and electrolytes and asses for signs and symptoms of dehydration. Also the nurse should monitor the blood pressure, pulse, and respirations. The nurse should asses for hyperglycemia, adventitious, breath sounds, and papillary reflexes. It is also necessary to asses for hypersensitivity to glycerin.
7. Personal thoughts about this drug or herb: What I found interesting about this drug is the certain adverse effects that could possibly happen from taking this glaucoma medication, it could cause nausea, pain, and confusion, vomiting just to name a few. It amazing how taking a eye medication could cause systemic effects.
1.pharmacokinetics: The intravenous preparation has an onset of action in 10 minutes with a peak of action in 30 minutes and durations of 4 to 5 hours. Onset action for oral preparation varies with a peak od action 60 to 90 minutes and the same duration action. The intravenous and oral preparations are absorbed rapidly and distributed to the kidneys, gallbladder, liver, lungs, gynecological or prostate tissue, and cerebrospinal fluid. It is 20 to 40% protein bound, and partain metabolism take place in the liver . Ther serum half life is 3 to 5 hours with normal renal function. The excretion of the drugs occurs in the urine and feces.